Heavy life challenge: Biology usually discriminates against heavy isotopes. Can we reverse, redirect, or exploit that tendency? Find a way to get plants and bacteria to preferentially incorporate heavy atomic isotopes.
Use microbes, algae, duckweed, or plant-cell cultures to produce deuterated and 13C/15N-labeled complex biomolecules that are expensive or impractical to synthesize chemically.
I know you're joking, but changes in isotopes mildly affect reduced mass and hence enzyme kinetics. Maize and other C4 plants already preferentially enrich themselves with 13C [0-3] which occasionally buggers up metabolomic experiments. Famously, a few drugs use 2H rather than natural abundance H typically in order to exploit a kinetic isotopic effect and get a better Km in their binding pocket [4].
Personally I don't see this as joking, I think this whole space is severely underfunded and could use some publicity and moonshot contests. I mean, think of it, the planet Earth is full of beautiful and diverse nanotechnology that can literally map-reduce complex behavior over individual molecules, and we do so little to use it for practical purposes. Even most advanced manufacturing methods we use are still simple things applied in bulk, counting matter by volume instead of as objects. There's lots of unexplored potential within reach, and here we actually know it can pan out, because we see these processes happening everywhere, all the time, all at once, all around us.
> Competitors must create an aircraft that is both lightweight and powerful – lifting at least 4x its weight while flying a 5-nautical-mile circuit course.
I'd make it 50NM. 5 is way too easy to bullshit with edge case engineering. Alternatively, set a minimum payload capacity of something like 100kg.
Maybe "edge case engineering" is precisely what they're looking for? Get people to think about beating the rules with cheesy strategies, in hopes some of those could, with some cleverness, scale up and evolve into proper, broad-range solution - or at least become a key previously-missing component of one. But even if it can't, very narrow capabilities can still be useful too; military isn't beyond doing silly things if they offer enough tactical advantage (enough to offset extra burden on logistics, at least).
The military is waking up to the need to adapt frontline logistics. With killrates of 90% for traditional trucks in the Ukraine war, without resupply missions by UAVs/UGVs holding positions is impossible now.
on foot (not 20km, usually its something like 3-5km AFAIK, 20km is the width of both sides strongpoints + no-mans-land between), or on some fast and agile one-way craft: motorcycles, buggies, e-bikes
the key idea is that you need something which can get you onto the enemy position either before hunter drones take off, or that a drone won't take out the whole complement, hence the uselessness of trucks
going on foot is not really due to the human wave nature of the attacks, but rather its like WW1 stosstruppen - they use whatever cover they can find and a squad of 4 on foot is much easier to go through bushes used as cover or when weather is not suitable for flying
of note here is that trucks were not really used for transport on the tactical level on the frontline, however lately (with drones from destinus) logistics runs in the rear have also become a problem even 100km+ deep - thats where the 90% killrate figure comes from
> however lately (with drones from destinus) logistics runs in the rear have also become a problem even 100km+ deep
That is quite interesting but in light of that my original question remains (except shifted 100 km back) what about troop transport? Are the combatants suffering a 90% killrate on all their large vehicles near the front or if not then what is special about logistics runs?
Also .. if that were the case russia would not find volunteers anymore, as the large majority of russian soldiers in Ukraine are there by free will, not because they were force drafted.
This is being announced to us or everyone right now? It's only around 10 weeks away: that seems surprisingly close. Have some folk already been made aware & have they had time to build for this DARPA Challenges? Generally I think of them as longer running challenges.
> Generally I think of them as longer running challenges.
Given how outlandish the ratio requirement is compared to currently available products I expect this one will be recurring for at least a few years similar to what happened with the self driving challenge 20ish years ago.
I saw https://www.youtube.com/watch?v=tohImHa4f5U (Hoarder Sam, "I'm building a drone for the DARPA lift challenge") the other day and it was a pretty good discussion of the "shape of the envelope" of the problem (and what kind of lift ratios actually exist in modern air vehicles), and particularly how they've set up the constraints to eliminate a bunch of "easy" approaches.
It also reminded me that for the first round of the self-driving grand challenge, none of the vehicles even completed the course :-) They really are trying to encourage "out of the box", or at least "not in the obvious box", designs...
It's Heavy Lift, not life
Heavy life challenge: Biology usually discriminates against heavy isotopes. Can we reverse, redirect, or exploit that tendency? Find a way to get plants and bacteria to preferentially incorporate heavy atomic isotopes.
Use microbes, algae, duckweed, or plant-cell cultures to produce deuterated and 13C/15N-labeled complex biomolecules that are expensive or impractical to synthesize chemically.
Could be fun, honestly.
I know you're joking, but changes in isotopes mildly affect reduced mass and hence enzyme kinetics. Maize and other C4 plants already preferentially enrich themselves with 13C [0-3] which occasionally buggers up metabolomic experiments. Famously, a few drugs use 2H rather than natural abundance H typically in order to exploit a kinetic isotopic effect and get a better Km in their binding pocket [4].
[0] https://en.wikipedia.org/wiki/Fractionation_of_carbon_isotop... [1] https://pubmed.ncbi.nlm.nih.gov/7577891/ [2] https://pubmed.ncbi.nlm.nih.gov/1734681/ [3] https://en.wikipedia.org/wiki/List_of_C4_plants [4] https://en.wikipedia.org/wiki/Deuterated_drug#Examples
Personally I don't see this as joking, I think this whole space is severely underfunded and could use some publicity and moonshot contests. I mean, think of it, the planet Earth is full of beautiful and diverse nanotechnology that can literally map-reduce complex behavior over individual molecules, and we do so little to use it for practical purposes. Even most advanced manufacturing methods we use are still simple things applied in bulk, counting matter by volume instead of as objects. There's lots of unexplored potential within reach, and here we actually know it can pan out, because we see these processes happening everywhere, all the time, all at once, all around us.
When life gets tough...
Contact DARPA for a lift !
CATL is working on 12000 Wh/kg air batteries, they will solve this problem, give them the prize.
> Competitors must create an aircraft that is both lightweight and powerful – lifting at least 4x its weight while flying a 5-nautical-mile circuit course.
I'd make it 50NM. 5 is way too easy to bullshit with edge case engineering. Alternatively, set a minimum payload capacity of something like 100kg.
Maybe "edge case engineering" is precisely what they're looking for? Get people to think about beating the rules with cheesy strategies, in hopes some of those could, with some cleverness, scale up and evolve into proper, broad-range solution - or at least become a key previously-missing component of one. But even if it can't, very narrow capabilities can still be useful too; military isn't beyond doing silly things if they offer enough tactical advantage (enough to offset extra burden on logistics, at least).
Giant hot air balloon for lift + 4 rotors for steering? It wouldn't be fast, but it might work [in low wind conditions].
Rules exclude that approach.
Darpa.mil got slashdotted? Wow. The folks who invented the internet...
The military is waking up to the need to adapt frontline logistics. With killrates of 90% for traditional trucks in the Ukraine war, without resupply missions by UAVs/UGVs holding positions is impossible now.
If the truck killrate is 90% what is it for troop transports? How do infantry get in and out of position?
on foot (not 20km, usually its something like 3-5km AFAIK, 20km is the width of both sides strongpoints + no-mans-land between), or on some fast and agile one-way craft: motorcycles, buggies, e-bikes
the key idea is that you need something which can get you onto the enemy position either before hunter drones take off, or that a drone won't take out the whole complement, hence the uselessness of trucks
going on foot is not really due to the human wave nature of the attacks, but rather its like WW1 stosstruppen - they use whatever cover they can find and a squad of 4 on foot is much easier to go through bushes used as cover or when weather is not suitable for flying
of note here is that trucks were not really used for transport on the tactical level on the frontline, however lately (with drones from destinus) logistics runs in the rear have also become a problem even 100km+ deep - thats where the 90% killrate figure comes from
> however lately (with drones from destinus) logistics runs in the rear have also become a problem even 100km+ deep
That is quite interesting but in light of that my original question remains (except shifted 100 km back) what about troop transport? Are the combatants suffering a 90% killrate on all their large vehicles near the front or if not then what is special about logistics runs?
> How do infantry get in and out of position?
They don't. Life expectancy of a Russian on the front line is hours. You just send in another wave.
If that were the case then there wouldn't be anyone there to receive the resupply to begin with.
Also .. if that were the case russia would not find volunteers anymore, as the large majority of russian soldiers in Ukraine are there by free will, not because they were force drafted.
Edit, I forgot, most are not aware of that:
https://www.rferl.org/a/russia-ukraine-conscripts-war-combat...
On foot, walking 20km+ to the position.
Armored carriers if avaiable.
Quads and dirt bikes afaik.
This is being announced to us or everyone right now? It's only around 10 weeks away: that seems surprisingly close. Have some folk already been made aware & have they had time to build for this DARPA Challenges? Generally I think of them as longer running challenges.
I'm looking forward to the DARPA Challenge to create a service where you can sign up to be emailed about new challenges. This one started October, 2025. More details at https://www.darpa.mil/research/challenges/lift/competitors
"Phase 1 | Launch
October 2025
Special Notice publishing (Oct. 23): DARPA publishes a Special Notice to broadly announce the Lift Challenge and solicit innovative design concepts.
Website launches (Oct. 23): DARPA publishes a Special Notice to broadly announce the Lift Challenge and solicit innovative design concepts.
Rules and prize announcement (Oct. 23): Detailed draft rules and prize structure are announced, specifying objective and subjective judging criteria."
> Generally I think of them as longer running challenges.
Given how outlandish the ratio requirement is compared to currently available products I expect this one will be recurring for at least a few years similar to what happened with the self driving challenge 20ish years ago.
this competition was announced October last year. IIRC registration ended sometime Q1 this year.
Typo in title: "lift" not "life"
cc @dang
Really just a battery challenge.
Possibly against laws of physics at energy density of 4x?
I saw https://www.youtube.com/watch?v=tohImHa4f5U (Hoarder Sam, "I'm building a drone for the DARPA lift challenge") the other day and it was a pretty good discussion of the "shape of the envelope" of the problem (and what kind of lift ratios actually exist in modern air vehicles), and particularly how they've set up the constraints to eliminate a bunch of "easy" approaches.
It also reminded me that for the first round of the self-driving grand challenge, none of the vehicles even completed the course :-) They really are trying to encourage "out of the box", or at least "not in the obvious box", designs...
You think your life is heavy, huh? You might want to check out this challenge...